Chemical Development, Sr. Principal Scientist - Process Chemist
Company: Cambrex
Location: Charles City
Posted on: May 23, 2023
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Job Description:
Company Information
You Matter to Cambrex.
Cambrex is a leading global contract development and manufacturing
organization (CDMO) that provides drug substance, drug product, and
analytical services across the entire drug lifecycle. With more
than 40 years of experience and a growing team of over 2,400
professionals servicing global clients, Cambrex is a trusted
partner in branded and generic markets for API and dosage form
development and manufacturing.
Your Work Matters.
At Cambrex, we strive to build a culture where all colleagues have
the opportunity to:
We're committed to attracting and nurturing a passionate team of
valued professionals in our fast-paced and growing company. We
offer a competitive benefits package that includes medical, dental,
vision, Life, LTD, retirement savings and more! Can we make this
broader language, so it fits in all markets, e.g., that includes
healthcare, life insurance, planning for retirement, and more!
Your Future Matters.
Known for our customer-focused scientific and manufacturing
excellence, as well as our strong commitment to quality and safety,
we offer a range of career and growth opportunities across our
global network of locations. Together with our customers, we aim to
improve the quality of life for patients around the world. Start a
career where You Matter by applying today!
Job Overview
Position is directed toward optimization of existing chemical
routes and development of alternate chemistry toward key synthetic
intermediates and APIs.-- Carries out multistep chemical synthesis
and product isolation/purification operations in the laboratory,
independently or as part of an integrated team.-- Chemist utilizes
modern analytical tools to determine identity and purity of
products made during projects.-- Communication with clients in
regular team meetings; prepares R&D reports at the conclusion
of projects.
Responsibilities
------------- Design and carry out multistep organic syntheses,
isolation, and purification of targeted products.
------------- Must possess a strong understanding of modern organic
synthesis methodologies.
------------- Must have a thorough understanding of modern
analytical and spectroscopic techniques and be able to interpret
the corresponding data and spectra.--
------------- Ability to conduct literature searches for specific
target compounds and be able to use the literature to base a design
of alternate routes to these compounds.-- Requires ongoing
professional development to keep abreast of current scientific
literature and discuss these findings with colleagues.
------------- Must demonstrate a proficiency to carry out
laboratory syntheses and purification techniques on scales ranging
from milligrams to several kilograms, and design and implement
process modifications.
------------- Requires excellent time management with the ability
to manage projects on-time without supervision.
------------- Ability to author and review comprehensive reports at
the conclusion of projects for internal and customer use. --
------------- Mentor and direct research activities of junior staff
members.
------------- Work closely with other chemistry and analytical
laboratory staff to coordinate project activities and resource
usage.
------------- Work to ensure that a spirit of teamwork and
cooperation always exists within the group.
------------- Conduct laboratory operations in a safe manner.--
Maintain familiarity with the company's chemical hygiene plan.--
Exhibit safety awareness and safe work practices.
------------- Follow responsible actions regarding chemical
disposal.-- Maintain compliance with all regulations at the
federal, state, and local levels.
------------- Must demonstrate effective communication skills (both
interpersonal and presentations).-- Participate in project team
meetings with customers.
------------- Work closely with manufacturing and GMP operations to
coordinate project related equipment and activities.
All employees are required to adhere to EPA, DEA, FDA and cGMP
regulations as they relate to the operation of the Company; and to
adhere to all company safety rules and procedures.-- All employees
are expected to report to work regularly and promptly.-- Other
duties relating to departmental mission, not specifically detailed
in this section may be assigned.
Education, Experience & Licensing Requirements
Education/knowledge requirements
Ph.D. in Chemistry or related field with minimum 10 years of
experience or M.S. in Chemistry or related field with minimum 14
years of experience or B.S. degree in Chemistry or related field
with 18 years of experience in lab environment, pharmaceutical
experience preferred.
Demonstrated ability to transfer processes to commercial scale
manufacturing.
Excellent verbal and written communication/interpersonal skills,
organizational skills, and the ability to work in a diverse team
environment are essential. --
Position COMPETENCIES:
Organic Chemistry Knowledge: High level of understanding of
advanced theories in Organic Chemistry/Process Development.
Cross Discipline Knowledge: Good understanding of the principles of
cross-functional departments, including analytical chemistry and
engineering.
GMP/Regulatory Knowledge: High level demonstration of the GMP
controls and understanding of regulatory requirements; Solid
understanding of site SOPs, industrial CMC requirements, and
demonstrates an ability to steer clients toward best outcome.
Instrumentation: Very high-level understanding of front-line
technology in the field (HPLC, NMR, MS, automated reactor
platforms, in-situ reaction monitoring, etc.) strong ability to
train others and advanced troubleshooting ability.
Communication: Excellent written and oral communication skills,
often leading technical calls with clients.
Problem Solving:-- Demonstrated ability to perform root cause
analysis and solve problems.
Time Management: Very good organizational skills and time
management.-- Able to work on several key items at once including
two or more medium complexity projects at once.
Leadership: Strong demonstration of mentorship and development of
peers, partner lines and ability to support initiatives with other
sites.
Technical Documentation and Review: Strong ability to generate key
technical documents with minimal RFT issues and to review documents
for others.-- Basic ability to write new SOP, keep current lab
notebook while practicing GDP.
External Influence: Strong demonstrated ability to independently
steer client or technical teams; ability to redirect and point out
scope change; good ability to work with site leadership team and
steer local initiatives.
Industry Credibility and Rapport: Demonstrated reputation as a
leader within the Cambrex chemical development community.-- Good
publication record, where possible, and strong contributions to the
Cambrex portfolio.
Operational Excellence: Demonstrated ability to participate and
share leadership on local OE initiatives.
Change Orientation: Demonstrated contribution of input and ideas
for larger Cambrex system level changes.
Cambrex is an Equal Opportunity / Affirmative Action employer and
will consider all qualified applicants for employment without
regard to race, color, religion, gender, sexual orientation, gender
identity, national origin, age, protected veteran status, or
disability status.
Cambrex Charles City offers an extraordinary opportunity, a
competitive salary, and an exceptional benefits package including
medical, dental, vision care and prescription, life, LTD, STD;
401(k) with employer match; tuition reimbursement; and the 'Arthur
I. Mendolia Scholarship Program.' Relocation assistance will be
offered for this position.--
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Keywords: Cambrex, Rochester , Chemical Development, Sr. Principal Scientist - Process Chemist, Other , Charles City, Minnesota
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