RTP Research Fellow
Company: Mayo Clinic
Location: Rochester
Posted on: January 9, 2026
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Job Description:
Mayo Clinic is top-ranked in more specialties than any other
care provider according to U.S. News & World Report. As we work
together to put the needs of the patient first, we are also
dedicated to our employees, investing in competitive compensation
and comprehensive benefit plans – to take care of you and your
family, now and in the future. And with continuing education and
advancement opportunities at every turn, you can build a long,
successful career with Mayo Clinic. Benefits Highlights • Medical:
Multiple plan options. • Dental: Delta Dental or reimbursement
account for flexible coverage. • Vision: Affordable plan with
national network. • Pre-Tax Savings: HSA and FSAs for eligible
expenses. • Retirement: Competitive retirement package to secure
your future. Responsibilities This position opens for a project
focused on comprehending the pathogenesis of polycystic kidney
disease, the 1 monogenic human disease leading to kidney failure
and death. We integrate cultured cell lines, organoids, and animal
models to understand how primary cilia regulate the formation of
kidney cysts during development and aging. We welcome individuals
who are highly curious to molecular mechanisms underlying human
diseases and highly motivated and committed to explorative
mechanistic research. Common molecular and cellular techniques are
required, including molecular cloning, mutagenesis, cell culture
and transfection, and immunoblotting. Experience on recombinant
protein expression and pull-down assays would be beneficial.
Candidates familiar with various microscope imaging techniques
especially immunofluorescence microscopy are highly encouraged to
apply. The project also involves proteomics studies, as well as
investigating disease phenotype in established mouse models using
MRI imaging and histological analyses. This lab is affiliated with
the Mayo Clinic Translational PKD Center and closely collaborates
with its world-renown PKD researchers and physicians. Succeeding
candidate will have full access to research tools and the
state-of-the-art technical services available at the PKD Center,
including patient samples and disease models that can be used for
pre-clinical studies if promising drug targets are defined. While
we greatly appreciate the independent problem-solving ability that
is critical for research, we do recognize the uniqueness of each
lab member and encourage teamwork and collaboration, devoting to
cultivate a supportive environment to promote personal growth. A
Research Fellow position in Life Sciences (LS) will require
knowledge of either clinical-based research or laboratory-based
research often obtained from a postdoctoral program. A Research
Fellow at Mayo Clinic is a temporary position intended to provide
training and education in research. Individuals will train in the
research program of a Mayo Clinic principal investigator. Qualified
individuals will demonstrate the potential for research as
evidenced by their training and peer-reviewed publications and
should become competitive for national research grants. Proof of
English proficiency is required for J-1 Short-Term Scholars,
Research Scholars, Professors, Specialists, and Student Interns
sponsored by Mayo Clinic. Qualifications Must have a Ph.D., M.D.,
or equivalent doctoral degree in a field deemed relevant by the
program. Research Fellow is appropriate for individuals who have
completed no more than one prior postdoctoral fellowship, at Mayo
Clinic or elsewhere.
Keywords: Mayo Clinic, Rochester , RTP Research Fellow, Science, Research & Development , Rochester, Minnesota
