IT Application Analyst

Company: Mayo Clinic
Location: Rochester
Posted on: March 26, 2026

Job Description:

Mayo Clinic’s tech culture is rooted in passion for technology, embraces innovative thinking and strives for high performance. Our teams drive change in health care through comprehensive connected health and digital transformation strategies. Some examples of our major initiatives are: • Utilizing artificial intelligence and machine learning principles to develop next generation patient centric care systems • Transforming the practice by applying data science techniques to discover new approaches to health care delivery • Leveraging Enterprise Architecture to construct integration centricity, promote data liquidity, and provide innovation support This transformation creates, connects and applies integrated knowledge to deliver the best health care, health guidance and health information to patients, customers, partners, providers, employees anywhere and anytime so the needs of the patient come first. Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. Benefits Highlights • Medical: Multiple plan options. • Dental: Delta Dental or reimbursement account for flexible coverage. • Vision: Affordable plan with national network. • Pre-Tax Savings: HSA and FSAs for eligible expenses. • Retirement: Competitive retirement package to secure your future. Responsibilities The Clinical Decision Support Team within the EHR Technology Domain is seeking an IT Application Analyst to support Epic Clinical Decision Support (CDS) functionality, including emerging capabilities in Epic Cognitive Computing. Clinical Decision Support tools are used across the Mayo enterprise and rely heavily on integration with a wide range of Epic applications, including Orders, Clinical Documentation, ASAP, Ambulatory, Healthy Planet, Anesthesia, and Genomics (including pharmacogenomics and genomic indicators). These integrations require complex system design and build, as well as strong partnerships with Informatics, clinical stakeholders, and practice liaisons. This role supports both foundational and advanced CDS capabilities. Core responsibilities include the design, build, and maintenance of Our Practice Advisories (OPAs, formerly BestPractice Advisories [BPAs]), as well as other CDS interventions such as Care Paths and Health Maintenance. These tools play a critical role in delivering timely, actionable guidance within clinical workflows. In addition, this position will contribute to the advancement of Epic Cognitive Computing, supporting the design, implementation, and optimization of intelligent decision support solutions. This includes leveraging advanced CDS capabilities to enhance clinical decision-making, improve patient outcomes, and enable more data-driven and precision medicine approaches to care delivery across the enterprise. The position requires a high level of analytical and problem-solving skills, strong organizational capabilities, sound judgment and decision-making, and excellent verbal and written communication skills. The successful candidate will demonstrate the ability to work collaboratively across multidisciplinary teams and manage complex, integrated system workflows. This vacancy is not eligible for sponsorship/we will not sponsor or transfer visas for this position. Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program. Qualifications • Bachelor’s degree or Associates Degree with 2 years’ experience in business analysis. Vendor application certification may be required. Preferred Qualifications: • Epic certification in one or more of the following applications: EpicCare Inpatient Orders, Epic Clinical Documentation, EpicCare Ambulatory, ASAP (Emergency Department), or Healthy Planet • Completion of Epic badges such as Clinical Decision Support: BestPractice Advisories (BPA/OPA), Health Maintenance, or Cognitive Computing, and/or Epic Genomics certification is a plus.

Keywords: Mayo Clinic, Rochester , IT Application Analyst, Healthcare , Rochester, Minnesota